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Modeling the site-specific variation of selection patterns along lineages
The unambiguous footprint of positive Darwinian selection in protein-coding DNA sequences is revealed by an excess of nonsynonymous substitutions over synonymous substitutions compared with the neutral expectation. Methods for analyzing the patterns of nonsynonymous and synonymous substitutions usua...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516501/ https://ncbi.nlm.nih.gov/pubmed/15326304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402177101 |
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