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Modeling the site-specific variation of selection patterns along lineages

The unambiguous footprint of positive Darwinian selection in protein-coding DNA sequences is revealed by an excess of nonsynonymous substitutions over synonymous substitutions compared with the neutral expectation. Methods for analyzing the patterns of nonsynonymous and synonymous substitutions usua...

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Main Authors: Guindon, Stéphane, Rodrigo, Allen G., Dyer, Kelly A., Huelsenbeck, John P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2004
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC516501/
https://ncbi.nlm.nih.gov/pubmed/15326304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402177101
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