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Modeling the site-specific variation of selection patterns along lineages

The unambiguous footprint of positive Darwinian selection in protein-coding DNA sequences is revealed by an excess of nonsynonymous substitutions over synonymous substitutions compared with the neutral expectation. Methods for analyzing the patterns of nonsynonymous and synonymous substitutions usua...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Guindon, Stéphane, Rodrigo, Allen G., Dyer, Kelly A., Huelsenbeck, John P.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516501/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15326304/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402177101
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