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Ion Mobility-Mass Spectrometry Analysis of Crosslinked Intact Multiprotein Complexes: Enhanced Gas-phase Stabilities and Altered Dissociation Pathways

Analysis of protein complexes by ion mobility-mass spectrometry is a valuable method for the rapid assessment of complex composition, binding stoichiometries, and structures. However, capturing labile, unknown protein assemblies directly from cells remains a challenge for the technology. Furthermore...

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Bibliografische gegevens
Gepubliceerd in:Anal Chem
Hoofdauteurs: Samulak, Billy M., Niu, Shuai, Andrews, Philip C., Ruotolo, Brandon T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164941/
https://ncbi.nlm.nih.gov/pubmed/27078797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b00518
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