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Ion Mobility-Mass Spectrometry Analysis of Crosslinked Intact Multiprotein Complexes: Enhanced Gas-phase Stabilities and Altered Dissociation Pathways
Analysis of protein complexes by ion mobility-mass spectrometry is a valuable method for the rapid assessment of complex composition, binding stoichiometries, and structures. However, capturing labile, unknown protein assemblies directly from cells remains a challenge for the technology. Furthermore...
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Publié dans: | Anal Chem |
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Auteurs principaux: | , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5164941/ https://ncbi.nlm.nih.gov/pubmed/27078797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b00518 |
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