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Identification of G-quadruplexes in long functional RNAs using 7-deaza-Guanine RNA

RNA G-quadruplex (G4) structures are thought to affect biological processes, including translation and pre-mRNA splicing, but it is not possible at present to demonstrate that they form naturally at specific sequences within long functional RNA molecules. We have developed a novel strategy, footprin...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Weldon, Carika, Behm-Ansmant, Isabelle, Hurley, Laurence H., Burley, Glenn A., Branlant, Christiane, Eperon, Ian C., Dominguez, Cyril
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164935/
https://ncbi.nlm.nih.gov/pubmed/27820800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2228
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