Homocysteine Activates B Cells via Regulating PKM2-Dependent Metabolic Reprogramming

The overactivation of immune cells plays an important role in the pathogenesis of hyperhomocysteinemia (HHcy)-accelerated atherosclerosis. Homocysteine (Hcy) activates B cell proliferation and Ab secretion; however, the underlying mechanisms for these effects remain largely unknown. Metabolic reprog...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Deng, Jiacheng, Lü, Silin, Liu, Huiying, Liu, Bo, Jiang, Changtao, Xu, Qingbo, Feng, Juan, Wang, Xian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AAI 2017
Gaiak:
Immune Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164882/
https://ncbi.nlm.nih.gov/pubmed/27903739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600613
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