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NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor
The corticotropin-releasing factor (CRF) ligand family has diverse effects on the CNS, including the modulation of the stress response. The ligands' effects are mediated by binding to CRF G protein-coupled receptors. We have determined the 3D NMR structure of the N-terminal extracellular domain...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516482/ https://ncbi.nlm.nih.gov/pubmed/15326300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404702101 |
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