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Multiple Domains of the Jaagsiekte Sheep Retrovirus Envelope Protein Are Required for Transformation of Rodent Fibroblasts

Jaagsiekte sheep retrovirus (JSRV) is an exogenous retrovirus of sheep that induces a contagious lung cancer, ovine pulmonary adenocarcinoma. We previously showed that the gene encoding JSRV envelope protein (Env) appears to function as an oncogene, since it can transform mouse NIH 3T3 cells. The cy...

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Detalles Bibliográficos
Main Authors: Hofacre, Andrew, Fan, Hung
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC516437/
https://ncbi.nlm.nih.gov/pubmed/15367614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10479-10489.2004
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