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Multiple Domains of the Jaagsiekte Sheep Retrovirus Envelope Protein Are Required for Transformation of Rodent Fibroblasts

Jaagsiekte sheep retrovirus (JSRV) is an exogenous retrovirus of sheep that induces a contagious lung cancer, ovine pulmonary adenocarcinoma. We previously showed that the gene encoding JSRV envelope protein (Env) appears to function as an oncogene, since it can transform mouse NIH 3T3 cells. The cy...

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Autors principals: Hofacre, Andrew, Fan, Hung
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516437/
https://ncbi.nlm.nih.gov/pubmed/15367614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10479-10489.2004
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