T-Cell Responses to the M3 Immune Evasion Protein of Murid Gammaherpesvirus 68 Are Partially Protective and Induced with Lytic Antigen Kinetics

DNA vaccination with the M3 gene, encoding an immune evasion molecule expressed during both the acute lytic and persistent phases of murid gammaherpesvirus 68 infection, yielded a significantly lower titer of virus in the lung than controls. The protection seen was dependent on T cells, and we mappe...

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Bibliografiska uppgifter
Huvudupphovsmän: Obar, Joshua J., Donovan, Douglas C., Crist, Sarah G., Silvia, Ondine, Stewart, James P., Usherwood, Edward J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC516430/
https://ncbi.nlm.nih.gov/pubmed/15367651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10829-10832.2004
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