T-Cell Responses to the M3 Immune Evasion Protein of Murid Gammaherpesvirus 68 Are Partially Protective and Induced with Lytic Antigen Kinetics

DNA vaccination with the M3 gene, encoding an immune evasion molecule expressed during both the acute lytic and persistent phases of murid gammaherpesvirus 68 infection, yielded a significantly lower titer of virus in the lung than controls. The protection seen was dependent on T cells, and we mappe...

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Hlavní autoři: Obar, Joshua J., Donovan, Douglas C., Crist, Sarah G., Silvia, Ondine, Stewart, James P., Usherwood, Edward J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC516430/
https://ncbi.nlm.nih.gov/pubmed/15367651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10829-10832.2004
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