Human Macrophages, but Not Dendritic Cells, Are Activated and Produce Alpha/Beta Interferons in Response to Mopeia Virus Infection

Lassa virus (LV) and Mopeia virus (MV) are closely related members of the Arenavirus genus, sharing 75% amino acid sequence identity. However, LV causes hemorrhagic fever in humans and nonhuman primates, whereas MV cannot induce disease. We have previously shown that antigen-presenting cells (APC)—m...

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Bibliographic Details
Main Authors: Pannetier, Delphine, Faure, Caroline, Georges-Courbot, Marie-Claude, Deubel, Vincent, Baize, Sylvain
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC516411/
https://ncbi.nlm.nih.gov/pubmed/15367618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10516-10524.2004
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