Enhanced Cytoplasmic Sequestration of the Nuclear Export Receptor CRM1 by NS2 Mutations Developed in the Host Regulates Parvovirus Fitness

To investigate whether a DNA virus can evade passive immunotherapy with a polyclonal antiserum, we analyzed the protection of a neutralizing capsid antiserum against a lethal infection of the immunosuppressive strain of the parvovirus minute virus of mice (MVMi) in 42 immunodeficient mice over a per...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: López-Bueno, Alberto, Valle, Noelia, Gallego, Jesús M., Pérez, Joel, Almendral, José M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516389/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15367634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.19.10674-10684.2004
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