Enhanced Cytoplasmic Sequestration of the Nuclear Export Receptor CRM1 by NS2 Mutations Developed in the Host Regulates Parvovirus Fitness

To investigate whether a DNA virus can evade passive immunotherapy with a polyclonal antiserum, we analyzed the protection of a neutralizing capsid antiserum against a lethal infection of the immunosuppressive strain of the parvovirus minute virus of mice (MVMi) in 42 immunodeficient mice over a per...

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Detalhes bibliográficos
Main Authors: López-Bueno, Alberto, Valle, Noelia, Gallego, Jesús M., Pérez, Joel, Almendral, José M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516389/
https://ncbi.nlm.nih.gov/pubmed/15367634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10674-10684.2004
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