Rapid Detection of Isoniazid and Rifampin Resistance Mutations in Mycobacterium tuberculosis Complex from Cultures or Smear-Positive Sputa by Use of Molecular Beacons

The slow-growing nature of Mycobacterium tuberculosis complex hinders the improvement of turnaround time for phenotypic drug susceptibility testing. We designed a set of molecular beacons for the detection of isoniazid and rifampin resistance mutations in M. tuberculosis complex organisms from cultu...

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Autors principals: Lin, S.-Y. Grace, Probert, William, Lo, Melanie, Desmond, Edward
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Mycobacteriology and Aerobic Actinomycetes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516347/
https://ncbi.nlm.nih.gov/pubmed/15365012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.9.4204-4208.2004
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