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A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming

Sexual reproduction culminates in a totipotent zygote with the potential to produce a whole organism. Sperm chromatin reorganization and epigenetic reprogramming that alter DNA and histone modifications generate a totipotent embryo. Active DNA demethylation of the paternal genome has been proposed t...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Ladstätter, Sabrina, Tachibana-Konwalski, Kikuë
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161750/
https://ncbi.nlm.nih.gov/pubmed/27916276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.009
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