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Nickel-Catalyzed Chemo- and Enantioselective Coupling Between Cyclobutanones and Allenes: Rapid Synthesis of [3.2.2] Bicycles

Herein an intramolecular Ni-catalyzed (4+2) coupling between cyclobutanones and allenes via C–C cleavage is reported, which provides a distinct approach to access [3.2.2] bicyclic scaffolds that are challenging to prepare through conventional approaches. The reaction is efficient, chemoselective and...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Zhou, Xuan, Dong, Guangbin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161747/
https://ncbi.nlm.nih.gov/pubmed/27813276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609489
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