Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas

Many solid cancers have an expanded CD44(+/hi)/CD24(−/low) cancer stem cell (CSC) population, which are relatively chemoresistant and drive recurrence and metastasis. Achieving a more durable response requires the development of therapies that specifically target CSCs. Recent evidence indicated that...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Stem Cell Reports
Hlavní autoři: Bogachek, Maria V., Park, Jung M., De Andrade, James P., Lorenzen, Allison W., Kulak, Mikhail V., White, Jeffrey R., Gu, Vivian W., Wu, Vincent T., Weigel, Ronald J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161532/
https://ncbi.nlm.nih.gov/pubmed/27916539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.11.001
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky