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STRUCTURAL AND BIOCHEMICAL ANALYSIS OF PROTEIN-PROTEIN INTERACTIONS BETWEEN THE ACYL-CARRIER PROTEIN AND PRODUCT TEMPLATE DOMAIN
In fungal non-reducing polyketide synthases (NR-PKS), the acyl-carrier protein (ACP) carries the growing polyketide intermediate through iterative rounds of elongation, cyclization and product release. This process occurs through a controlled, yet enigmatic coordination of the ACP with its partner e...
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| 發表在: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5161458/ https://ncbi.nlm.nih.gov/pubmed/27653519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201605401 |
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