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Detecting Sources of Transcriptional Heterogeneity in Large-Scale RNA-Seq Data Sets

Gene expression levels are dynamic molecular phenotypes that respond to biological, environmental, and technical perturbations. Here we use a novel replicate-classifier approach for discovering transcriptional signatures and apply it to the Genotype-Tissue Expression data set. We identified many fac...

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發表在:Genetics
Main Authors: Searle, Brian C., Gittelman, Rachel M., Manor, Ohad, Akey, Joshua M.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161273/
https://ncbi.nlm.nih.gov/pubmed/27729424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.193714
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