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Does autophagy mediate cardiac myocyte death during stress?

Although autophagy generally promotes survival of cardiac myocytes, it also promotes death of cardiac myocytes in some conditions. Here we describe how activation of autophagy leads to death of cardiac myocytes, introduce a novel concept of autosis, a unique form of cell death by autophagy, and disc...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Nah, Jihoon, Fernandez, Alvaro, Kitsis, Richard N, Levine, Beth, Sadoshima, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161244/
https://ncbi.nlm.nih.gov/pubmed/27688304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.309765
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