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Does autophagy mediate cardiac myocyte death during stress?

Although autophagy generally promotes survival of cardiac myocytes, it also promotes death of cardiac myocytes in some conditions. Here we describe how activation of autophagy leads to death of cardiac myocytes, introduce a novel concept of autosis, a unique form of cell death by autophagy, and disc...

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Détails bibliographiques
Publié dans:Circ Res
Auteurs principaux: Nah, Jihoon, Fernandez, Alvaro, Kitsis, Richard N, Levine, Beth, Sadoshima, Junichi
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161244/
https://ncbi.nlm.nih.gov/pubmed/27688304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.309765
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