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Cis→Trans Isomerization of Pro(7) in Oxytocin Regulates Zn(2+) Binding

Ion mobility/mass spectrometry techniques are employed to investigate the binding of Zn(2+) to the nine-residue peptide hormone oxytocin (OT, Cys(1)-Tyr(2)-Ile(3)-Gln(4)-Asn(5)-Cys(6)-Pro(7)-Leu(8)-Gly(9)-NH(2), having a disulfide bond between Cys(1) and Cys(6) residues). Zn(2+) binding to OT is kno...

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Bibliografski detalji
Izdano u:J Am Soc Mass Spectrom
Glavni autori: Fuller, Daniel R., Glover, Matthew S., Pierson, Nicholas A., Kim, DoYong, Russell, David H., Clemmer, David E.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161230/
https://ncbi.nlm.nih.gov/pubmed/27154022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-016-1410-4
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