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Cis→Trans Isomerization of Pro(7) in Oxytocin Regulates Zn(2+) Binding
Ion mobility/mass spectrometry techniques are employed to investigate the binding of Zn(2+) to the nine-residue peptide hormone oxytocin (OT, Cys(1)-Tyr(2)-Ile(3)-Gln(4)-Asn(5)-Cys(6)-Pro(7)-Leu(8)-Gly(9)-NH(2), having a disulfide bond between Cys(1) and Cys(6) residues). Zn(2+) binding to OT is kno...
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| Publicado no: | J Am Soc Mass Spectrom |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5161230/ https://ncbi.nlm.nih.gov/pubmed/27154022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-016-1410-4 |
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