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Simultaneous paralogue knockout using a CRISPR-concatemer in mouse small intestinal organoids
Approaches based on genetic modification have been invaluable for investigating a wide array of biological processes, with gain- and loss-of-function approaches frequently used to investigate gene function. However, the presence of paralogues, and hence possible genetic compensation, for many genes...
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| Publicado no: | Dev Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5161140/ https://ncbi.nlm.nih.gov/pubmed/27983963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.10.016 |
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