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Semi-automated, single-band peak-fitting analysis of hydroxyl radical nucleic acid footprint autoradiograms for the quantitative analysis of transitions

Hydroxyl radical footprinting can probe the solvent accessibility of the ribose moiety of the individual nucleotides of DNA and RNA. Semi-automated analytical tools are presented for the quantitative analyses of nucleic acid footprint transitions in which processes such as folding or ligand binding...

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Autori principali: Takamoto, Keiji, Chance, Mark R., Brenowitz, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC516076/
https://ncbi.nlm.nih.gov/pubmed/15319447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh117
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