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Semi-automated, single-band peak-fitting analysis of hydroxyl radical nucleic acid footprint autoradiograms for the quantitative analysis of transitions

Hydroxyl radical footprinting can probe the solvent accessibility of the ribose moiety of the individual nucleotides of DNA and RNA. Semi-automated analytical tools are presented for the quantitative analyses of nucleic acid footprint transitions in which processes such as folding or ligand binding...

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Main Authors: Takamoto, Keiji, Chance, Mark R., Brenowitz, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC516076/
https://ncbi.nlm.nih.gov/pubmed/15319447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh117
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