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Nuclear reprogramming of cancer stem cells: Corrupting the epigenetic code of cell identity with oncometabolites

Generation of cancer stem cell (CSC)-like cells might occur through metabolic corruption of the epigenetic codes that govern cell identity. We recently identified how archetypal oncometabolites, without altering the baseline expression of endogenous stem cell maintenance genes but endowing cells wit...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Menendez, Javier A., Alarcón, Tomás
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5160399/
https://ncbi.nlm.nih.gov/pubmed/28090573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1160854
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