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Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia
BACKGROUND: Farnesyl protein transferase inhibitors (FTIs) were originally developed to inhibit oncogenic ras, however it is now clear that there are several other potential targets for this drug class. The FTI tipifarnib (ZARNESTRA™, R115777) has recently demonstrated clinical responses in adults w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516036/ https://ncbi.nlm.nih.gov/pubmed/15329151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-56 |
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