A Clickable Analogue of Ketamine Retains NMDA Receptor Activity, Psychoactivity, and Accumulates in Neurons

Ketamine is a psychotomimetic and antidepressant drug. Although antagonism of cell-surface NMDA receptors (NMDARs) may trigger ketamine’s psychoactive effects, ketamine or its major metabolite norketamine could act intracellularly to produce some behavioral effects. To explore the viability of this...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Emnett, Christine, Li, Hairong, Jiang, Xiaoping, Benz, Ann, Boggiano, Joseph, Conyers, Sara, Wozniak, David F., Zorumski, Charles F., Reichert, David E., Mennerick, Steven
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159840/
https://ncbi.nlm.nih.gov/pubmed/27982047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38808
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge