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A Clickable Analogue of Ketamine Retains NMDA Receptor Activity, Psychoactivity, and Accumulates in Neurons

Ketamine is a psychotomimetic and antidepressant drug. Although antagonism of cell-surface NMDA receptors (NMDARs) may trigger ketamine’s psychoactive effects, ketamine or its major metabolite norketamine could act intracellularly to produce some behavioral effects. To explore the viability of this...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Emnett, Christine, Li, Hairong, Jiang, Xiaoping, Benz, Ann, Boggiano, Joseph, Conyers, Sara, Wozniak, David F., Zorumski, Charles F., Reichert, David E., Mennerick, Steven
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159840/
https://ncbi.nlm.nih.gov/pubmed/27982047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38808
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