Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2

Cyclin G1 (CycG1) and Cyclin G2 (CycG2) play similar roles during the DNA damage response (DDR), but their detailed roles remain elusive. To investigate their distinct roles, we generated knockout mice deficient in CycG1 (G1KO) or CycG2 (G2KO), as well as double knockout mice (DKO) deficient in both...

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Udgivet i:Sci Rep
Main Authors: Ohno, Shouichi, Ikeda, Jun-ichiro, Naito, Yoko, Okuzaki, Daisuke, Sasakura, Towa, Fukushima, Kohshiro, Nishikawa, Yukihiro, Ota, Kaori, Kato, Yorika, Wang, Mian, Torigata, Kosuke, Kasama, Takashi, Uchihashi, Toshihiro, Miura, Daisaku, Yabuta, Norikazu, Morii, Eiichi, Nojima, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159814/
https://ncbi.nlm.nih.gov/pubmed/27982046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39091
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