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Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells

Withaferin A (WA), a major bioactive component of the Indian herb Withania somnifera, induces cell death (apoptosis/necrosis) in multiple types of tumor cells, but the molecular mechanism underlying this cytotoxicity remains elusive. We report here that 2 μM WA induced cell death selectively in andr...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Nishikawa, Yukihiro, Okuzaki, Daisuke, Fukushima, Kohshiro, Mukai, Satomi, Ohno, Shouichi, Ozaki, Yuki, Yabuta, Norikazu, Nojima, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521694/
https://ncbi.nlm.nih.gov/pubmed/26230090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134137
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