Induction of a Cellular DNA Damage Response by Porcine Circovirus Type 2 Facilitates Viral Replication and Mediates Apoptotic Responses

Cellular DNA damage response (DDR) triggered by infection of DNA viruses mediate cell cycle checkpoint activation, DNA repair, or apoptosis induction. In the present study, infection of porcine circovirus type 2 (PCV2), which serves as a major etiological agent of PCV2-associated diseases (PCVAD), w...

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Publicat a:Sci Rep
Autors principals: Wei, Li, Zhu, Shanshan, Wang, Jing, Quan, Rong, Yan, Xu, Li, Zixue, Hou, Lei, Wang, Naidong, Yang, Yi, Jiang, Haijun, Liu, Jue
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159794/
https://ncbi.nlm.nih.gov/pubmed/27982097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39444
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