Induction of a Cellular DNA Damage Response by Porcine Circovirus Type 2 Facilitates Viral Replication and Mediates Apoptotic Responses

Cellular DNA damage response (DDR) triggered by infection of DNA viruses mediate cell cycle checkpoint activation, DNA repair, or apoptosis induction. In the present study, infection of porcine circovirus type 2 (PCV2), which serves as a major etiological agent of PCV2-associated diseases (PCVAD), w...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wei, Li, Zhu, Shanshan, Wang, Jing, Quan, Rong, Yan, Xu, Li, Zixue, Hou, Lei, Wang, Naidong, Yang, Yi, Jiang, Haijun, Liu, Jue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159794/
https://ncbi.nlm.nih.gov/pubmed/27982097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39444
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