Across-cohort QC analyses of GWAS summary statistics from complex traits

Genome-wide association studies (GWASs) have been successful in discovering SNP trait associations for many quantitative traits and common diseases. Typically, the effect sizes of SNP alleles are very small and this requires large genome-wide association meta-analyses (GWAMAs) to maximize statistica...

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Publicat a:Eur J Hum Genet
Autors principals: Chen, Guo-Bo, Lee, Sang Hong, Robinson, Matthew R, Trzaskowski, Maciej, Zhu, Zhi-Xiang, Winkler, Thomas W, Day, Felix R, Croteau-Chonka, Damien C, Wood, Andrew R, Locke, Adam E, Kutalik, Zoltán, Loos, Ruth J F, Frayling, Timothy M, Hirschhorn, Joel N, Yang, Jian, Wray, Naomi R, Visscher, Peter M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159754/
https://ncbi.nlm.nih.gov/pubmed/27552965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.106
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