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Steroidogenic Factor-1 and Human Disease

Steroidogenic factor-1 (SF-1) (Ad4BP, NR5A1) is a nuclear receptor that plays a key role in adrenal and reproductive development and function. Deletion of the gene encoding Sf-1 (Nr5a1) in mice results in severe developmental defects of the adrenal gland and gonad. Consequently, initial work on the...

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Bibliografiske detaljer
Udgivet i:Semin Reprod Med
Main Authors: El-Khairi, Ranna, Achermann, John C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159746/
https://ncbi.nlm.nih.gov/pubmed/23044873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0032-1324720
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