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DAX-1 (NR0B1) and steroidogenic factor-1 (SF-1, NR5A1) in human disease

DAX-1 (NR0B1) and SF-1 (NR5A1) are two nuclear receptor transcription factors that play a key role in human adrenal and reproductive development. Loss of DAX-1 function is classically associated with X-linked adrenal hypoplasia congenita. This condition typically affects boys and presents as primary...

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Publicado en:Best Pract Res Clin Endocrinol Metab
Autores principales: Suntharalingham, Jenifer P., Buonocore, Federica, Duncan, Andrew J., Achermann, John C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159745/
https://ncbi.nlm.nih.gov/pubmed/26303087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beem.2015.07.004
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