Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature

Many drugs have been reported to cause thrombotic microangiopathy (TMA), yet evidence supporting a direct association is often weak. In particular, TMA has been reported in association with recombinant type I interferon (IFN) therapies, with recent concern regarding the use of IFN in multiple sclero...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Blood
Κύριοι συγγραφείς: Kavanagh, David, McGlasson, Sarah, Jury, Alexa, Williams, Jac, Scolding, Neil, Bellamy, Chris, Gunther, Claudia, Ritchie, Diane, Gale, Daniel P., Kanwar, Yashpal S., Challis, Rachel, Buist, Holly, Overell, James, Weller, Belinda, Flossmann, Oliver, Blunden, Mark, Meyer, Eric P., Krucker, Thomas, Evans, Stephen J. W., Campbell, Iain L., Jackson, Andrew P., Chandran, Siddharthan, Hunt, David P. J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2016
Θέματα:
Platelets and Thrombopoiesis
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159705/
https://ncbi.nlm.nih.gov/pubmed/27663672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-715987
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