Thrombotic Microangiopathy in Inverted Formin 2–Mediated Renal Disease

The demonstration of impaired C regulation in the thrombotic microangiopathy (TMA) atypical hemolytic uremic syndrome (aHUS) resulted in the successful introduction of the C inhibitor eculizumab into clinical practice. C abnormalities account for approximately 50% of aHUS cases; however, mutations i...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Challis, Rachel C., Ring, Troels, Xu, Yaobo, Wong, Edwin K.S., Flossmann, Oliver, Roberts, Ian S.D., Ahmed, Saeed, Wetherall, Michael, Salkus, Giedrius, Brocklebank, Vicky, Fester, Julian, Strain, Lisa, Wilson, Valerie, Wood, Katrina M., Marchbank, Kevin J., Santibanez-Koref, Mauro, Goodship, Timothy H.J., Kavanagh, David
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2017
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373440/
https://ncbi.nlm.nih.gov/pubmed/27974406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015101189
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