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Altered biochemical specificity of G-quadruplexes with mutated tetrads
A fundamental motif in canonical nucleic acid structure is the base pair. Mutations that disrupt base pairs are typically destabilizing, but stability can often be restored by a second mutation that replaces the original base pair with an isosteric variant. Such concerted changes are a way to identi...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5159562/ https://ncbi.nlm.nih.gov/pubmed/27789695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw987 |
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