RNA2DNAlign: nucleotide resolution allele asymmetries through quantitative assessment of RNA and DNA paired sequencing data

We introduce RNA2DNAlign, a computational framework for quantitative assessment of allele counts across paired RNA and DNA sequencing datasets. RNA2DNAlign is based on quantitation of the relative abundance of variant and reference read counts, followed by binomial tests for genotype and allelic sta...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Movassagh, Mercedeh, Alomran, Nawaf, Mudvari, Prakriti, Dede, Merve, Dede, Cem, Kowsari, Kamran, Restrepo, Paula, Cauley, Edmund, Bahl, Sonali, Li, Muzi, Waterhouse, Wesley, Tsaneva-Atanasova, Krasimira, Edwards, Nathan, Horvath, Anelia
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159535/
https://ncbi.nlm.nih.gov/pubmed/27576531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw757
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