RNA2DNAlign: nucleotide resolution allele asymmetries through quantitative assessment of RNA and DNA paired sequencing data

We introduce RNA2DNAlign, a computational framework for quantitative assessment of allele counts across paired RNA and DNA sequencing datasets. RNA2DNAlign is based on quantitation of the relative abundance of variant and reference read counts, followed by binomial tests for genotype and allelic sta...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Movassagh, Mercedeh, Alomran, Nawaf, Mudvari, Prakriti, Dede, Merve, Dede, Cem, Kowsari, Kamran, Restrepo, Paula, Cauley, Edmund, Bahl, Sonali, Li, Muzi, Waterhouse, Wesley, Tsaneva-Atanasova, Krasimira, Edwards, Nathan, Horvath, Anelia
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159535/
https://ncbi.nlm.nih.gov/pubmed/27576531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw757
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