Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease

The U1 small nuclear (sn)RNA (U1) is a multifunctional ncRNA, known for its pivotal role in pre-mRNA splicing and regulation of RNA 3′ end processing events. We recently demonstrated that a new class of human U1-like snRNAs, the variant (v)U1 snRNAs (vU1s), also participate in pre-mRNA processing ev...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Vazquez-Arango, Pilar, Vowles, Jane, Browne, Cathy, Hartfield, Elizabeth, Fernandes, Hugo J. R., Mandefro, Berhan, Sareen, Dhruv, James, William, Wade-Martins, Richard, Cowley, Sally A., Murphy, Shona, O'Reilly, Dawn
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159530/
https://ncbi.nlm.nih.gov/pubmed/27536002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw711
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