Differentially expressed, variant U1 snRNAs regulate gene expression in human cells

Human U1 small nuclear (sn)RNA, required for splicing of pre-mRNA, is encoded by genes on chromosome 1 (1p36). Imperfect copies of these U1 snRNA genes, also located on chromosome 1 (1q12-21), were thought to be pseudogenes. However, many of these “variant” (v)U1 snRNA genes produce fully processed...

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Detalhes bibliográficos
Main Authors: O'Reilly, Dawn, Dienstbier, Martin, Cowley, Sally A., Vazquez, Pilar, Drożdż, Marek, Taylor, Stephen, James, William S., Murphy, Shona
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561869/
https://ncbi.nlm.nih.gov/pubmed/23070852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.142968.112
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