Antibodies that neutralize human beta interferon biologic activity recognize a linear epitope: analysis by synthetic peptide mapping.

The location of biologically relevant epitopes on recombinant human beta interferon in which Ser-17 replaces Cys-17 (rh[Ser17]IFN-beta) was evaluated by testing the immunoreactivity of antibodies against 159 sequential, overlapping octamer peptides. Three monoclonal antibodies (mAbs) that neutralize...

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Autores principales: Redlich, P N, Hoeprich, P D, Colby, C B, Grossberg, S E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC51589/
https://ncbi.nlm.nih.gov/pubmed/1708891
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