Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization
Summary: Broadly HIV-1 neutralizing VRC01 class antibodies target the CD4-binding site of Env. They are derived from VH1-2∗02 antibody heavy chains paired with rare light chains expressing 5-amino acid-long CDRL3s. They have been isolated from infected subjects but have not yet been elicited by immu...
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| Автори: | , , , , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2019-12-01
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| Серія: | Cell Reports |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S2211124719313932 |
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