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Pertussis Toxin Is a Robust and Selective Inhibitor of High Grade Glioma Cell Migration and Invasion

In high grade glioma (HGG), extensive tumor cell infiltration of normal brain typically precludes identifying effective margins for surgical resection or irradiation. Pertussis toxin (PT) is a multimeric complex that inactivates diverse G(i/o) G-protein coupled receptors (GPCRs). Despite the broad c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gilder, Andrew S., Wang, Lei, Natali, Letizia, Karimi-Mostowfi, Nicki, Brifault, Coralie, Gonias, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158192/
https://ncbi.nlm.nih.gov/pubmed/27977780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168418
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