Construction and characterization of a single-chain catalytic antibody.

The antigen-binding (Fab) fragment of the catalytic monoclonal antibody NPN43C9 has recently been cloned by using bacteriophage lambda. By inserting the variable regions of this Fab coding sequence into a (NH2)-VL-linker-VH-(COOH) construct (where VL and VH represent the heavy and light chain variab...

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Bibliographic Details
Main Authors: Gibbs, R A, Posner, B A, Filpula, D R, Dodd, S W, Finkelman, M A, Lee, T K, Wroble, M, Whitlow, M, Benkovic, S J
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC51581/
https://ncbi.nlm.nih.gov/pubmed/2023948
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