Construction and characterization of a single-chain catalytic antibody.

The antigen-binding (Fab) fragment of the catalytic monoclonal antibody NPN43C9 has recently been cloned by using bacteriophage lambda. By inserting the variable regions of this Fab coding sequence into a (NH2)-VL-linker-VH-(COOH) construct (where VL and VH represent the heavy and light chain variab...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gibbs, R A, Posner, B A, Filpula, D R, Dodd, S W, Finkelman, M A, Lee, T K, Wroble, M, Whitlow, M, Benkovic, S J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51581/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2023948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.9.4001
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