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Recent advances in the discovery and development of antibacterial agents targeting the cell-division protein FtsZ

With the emergence of multidrug-resistant bacterial strains, there is a dire need for new drug targets for antibacterial drug discovery and development. Filamentous temperature sensitive protein Z (FtsZ), is a GTP-dependent prokaryotic cell division protein, sharing less than 10% sequence identity w...

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Publicat a:Bioorg Med Chem
Autors principals: Haranahalli, Krupanandan, Tong, Simon, Ojima, Iwao
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157688/
https://ncbi.nlm.nih.gov/pubmed/27189886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.05.003
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