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Dendrobium alkaloids prevent Aβ(25–35)-induced neuronal and synaptic loss via promoting neurotrophic factors expression in mice

BACKGROUND: Neuronal and synaptic loss is the most important risk factor for cognitive impairment. Inhibiting neuronal apoptosis and preventing synaptic loss are promising therapeutic approaches for Alzheimer’s disease (AD). In this study, we investigate the protective effects of Dendrobium alkaloid...

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Bibliografiske detaljer
Udgivet i:PeerJ
Main Authors: Nie, Jing, Tian, Yong, Zhang, Yu, Lu, Yan-Liu, Li, Li-Sheng, Shi, Jing-Shan
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157189/
https://ncbi.nlm.nih.gov/pubmed/27994964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2739
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